Article
Intracellular transport and maturation of nascent low density lipoprotein receptor is blocked by mutation in the Ras-related GTP-binding protein, RAB1B.
Journal of receptor and signal transduction research - 1 Jan 2000
Castellano F, Wilson A L, Maltese W A
Abstract excerpt
The relationship between the Ras-related GTP-binding protein, Rab1B, and intracellular transport of nascent low density lipoprotein (LDL) receptor was studied in cultured human embryonic kidney cells (line 293) cotransfected with plasmids encoding the LDL-receptor and either wild-type Rab1B or a Rab1B mutant (N121I) known to act as a dominant suppressor of endogenous Rab1B function. [35S]Methionine pulse-chase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
