Article
Genetic mobility and distribution of tetracycline resistance determinants.
Ciba Foundation symposium - 1 Jan 1997
Roberts M C
Abstract excerpt
Since 1953, tetracycline-resistant bacteria have been found increasingly in humans, animals, food and the environment. Tetracycline resistance is normally due to the acquisition of new genes and is primarily due to either energy-dependent efflux of tetracycline or protection of the ribosomes from its action. Gram-negative efflux genes are frequently associated with conjugative plasmids, whereas Gram-positive...
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