Article
Role of Horizontal Gene Transfer in the Development of Multidrug Resistance in Haemophilus influenzae.
mSphere - 29 Jan 2020
Hegstad Kristin, Mylvaganam Haima, Janice Jessin, Josefsen Ellen, Sivertsen Audun, Skaare Dagfinn
Abstract excerpt
Haemophilus influenzae colonizes the respiratory tract in humans and causes both invasive and noninvasive infections. Resistance to extended-spectrum cephalosporins in H. influenzae is rare in Europe. In this study, we defined acquired resistance gene loci and ftsI mutations in multidrug-resistant (MDR) and/or PBP3-mediated beta-lactam-resistant (rPBP3) H. influenzae strains, intending to understand the mode of...
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