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Article

Pro-protein convertase gene expression in human breast cancer

11 Jun 1997

Abstract excerpt

As a first step towards elucidating the role that pro-protein convertases play in the growth regulation of breast cancer, we studied the gene expression of 6 known human convertase members (PC1/PC3, PC2, furin/PACE, PACE4, PC5/PC6 and PC7/LPC) in human breast cancer tumors and cell lines. PC1, furin, PACE4 and PC7 mRNAs were detected by reverse transcriptase-polymerase chain reaction (RT-PCR) amplification in all...

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PMID: 9185698
DOI: 10.1002/(sici)1097-0215(19970611)71:6<966::aid-ijc10>3.0.co;2-4

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