Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cladistic analysis of disease association with tyrosine hydroxylase: application to manic-depressive disease and alcoholism.

American journal of medical genetics - 31 May 1997

Lobos E A, Todd R D

Abstract excerpt

We evaluated the involvement of tyrosine hydroxylase (TH) mutations in susceptibility to manic-depressive disease (MDD) and alcoholism (ALC) with a cladistics-based association analysis. Eighty-one probands with MDD, 113 probands with alcoholism, and 80 normal controls were tested for differences in frequency of nine haplotypes at the TH locus. The haplotypes were comprised of four restriction fragment length...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Disease Susceptibility
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Haplotypes

Share to Models, Genetic

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 9184313
DOI: 10.1002/(sici)1096-8628(19970531)74:3<289::aid-ajmg10>3.0.co;2-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cladistic analysis of disease association with tyrosine hydroxylase: application to manic-depressive disease and alcoholism.PMID 9184313Read ↗

Association analysis in an evolutionary context: cladistic analysis of the DRD2 locus to test for association with alcoholism.Semantic proximity Read ↗

Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits.Semantic proximity Read ↗

Haplotypes of the monoamine oxidase genes and the risk for substance use disorders.Semantic proximity Read ↗

Cladistic analysis: its applications in association studies of complex diseases.Semantic proximity Read ↗

A genome-wide tree- and forest-based association analysis of comorbidity of alcoholism and smoking.Semantic proximity Read ↗

Tryptophan hydroxylase-1 gene variants associate with a group of suicidal borderline women.Semantic proximity Read ↗

Cladistic approaches to identifying determinants of variability in multifactorial phenotypes and the evolutionary significance of variation in the human genome.Semantic proximity Read ↗

Typologies of alcohol dependence. From Jellinek to genetics and beyond.Semantic proximity Read ↗

Manic depressive illness and tyrosine hydroxylase gene: linkage heterogeneity and association.Semantic proximity Read ↗

Association and haplotype analysis at the tyrosine hydroxylase locus in a combined German-British sample of manic depressive patients and controls.Semantic proximity Read ↗

Statistical performance of cladistic strategies for haplotype grouping in pharmacogenetics.Semantic proximity Read ↗

Haplotypes of dopamine and serotonin transporter genes are associated with antisocial personality disorder in alcoholics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.