Article
Dopaminergic phenotype induced by oestrogens in a human neuroblastoma cell line.
The European journal of neuroscience - 1 May 1997
Agrati P, Ma Z Q, Patrone C, Picotti G B, Pellicciari C, Bondiolotti G, Bottone M G, Maggi A
Abstract excerpt
Oestrogens are the key factor in the sexual differentiation of the mammalian brain and play an important role in the activity of selected areas of the mature brain. To pursue the study of oestrogen action on neural cells at the molecular level, we developed a human neuroblastoma cell line (SK-ER3) expressing the oestrogen receptor (ER). Treatment of these cells with 17beta-oestradiol causes growth arrest and...
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