Article
Neonatal lupus erythematosus: HLA-DR and -DQ distributions are different among the groups of anti-Ro/SSA-positive mothers with different neonatal outcomes.
The Journal of investigative dermatology - 1 Jun 1997
Miyagawa S, Shinohara K, Kidoguchi K, Fujita T, Fukumoto T, Yamashina Y, Hashimoto K, Yoshioka A, Sakurai S, Nishihara O, Shirai T
Abstract excerpt
Neonatal lupus erythematosus (NLE) is an antibody-mediated disorder of infants characterized by two major clinical manifestations; cutaneous lupus lesions and congenital heart block (CHB). The disease is associated with placentally transferred maternal anti-Ro/SSA and/or La/SSB antibodies. There is a tendency for the same disease expression to occur within a sibship. To reveal a possible association of class II...
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