Article
Different spatial and temporal interactions between Notch, wingless, and vestigial specify proximal and distal pattern elements of the wing in Drosophila.
Developmental biology - 15 Feb 1998
Klein T, Arias A M
Abstract excerpt
The wing of Drosophila is composed of a proximal element, the hinge, which attaches it to the thorax, and a distal one, the wing blade. The development of the wing is a complex process that requires the integration of cellular responses to two signaling systems centered along the anteroposterior and the dorsoventral axes. The genes Notch (N) and wingless (wg) play an important role in generating the information...
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