Article
C-kit mutations and mast cell disorders. A model of activating mutations of growth factor receptors.
Hematology and cell therapy - 1 Apr 1997
Pignon J M
Abstract excerpt
Mastocytosis are a group of diseases characterized by abnormal proliferation of mast cells. Various forms are observed in respect to the organ system involving, clinical manifestations, and association with hematological disorders. The c-kit proto-oncogene encodes for a receptor tyrosine kinase,...
Topics
- Animals
- Gene Expression Regulation
- Humans
- Mastocytosis
- Mice
- Mutation
- Proto-Oncogene Mas
- Proto-Oncogene Proteins c-kit
- Receptors, Growth Factor
