Article
Pathogenesis of prolactinomas.
Pituitary - 1 Jan 2005
Spada Anna, Mantovani Giovanna, Lania Andrea
Abstract excerpt
In recent years the demonstration that human pituitary adenomas are monoclonal in origin provides further evidence that pituitary neoplasia arise from the replication of a single mutated cell in which growth advantage results from either activation of proto-oncogenes or inactivation of tumor suppressor genes. However, with the exception of one RAS mutation identified in a single unusually aggressive prolactinoma...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.