Article
Enhanced co-stimulatory ability of synovial fluid accessory cells in rheumatoid arthritis.
British journal of rheumatology - 1 Apr 1997
Robertson S E, Young S P, Viner N J, Bacon P A
Abstract excerpt
We have established in vitro assays that allow the examination of co-stimulatory function of rheumatoid arthritis (RA) antigen-presenting cells (APC). Synovial fluid (SF) and peripheral blood (PB) APC co-stimulatory ability was compared in the activation of peptide-specific human T-cell clones. T-cell receptor (TCR) stimulation by peptide or anti-CD3 antibody allowed the direct comparison of SF and PB APC...
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