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Article

[Mechanisms of endogenous drug resistance acquisition by spontaneous chromosomal gene mutation].

Nihon rinsho. Japanese journal of clinical medicine - 1 May 1997

Fukuda H, Hiramatsu K

Abstract excerpt

Endogenous resistance in bacteria is caused by a change or loss of function and generally genetically recessive. However, this type of resistance acquisition are now prevalent in clinical setting. Chromosomal genes that afford endogenous resistance are the genes correlated with the target of the drug, the drug inactivating enzymes, and permeability of the molecules including the antibacterial agents. Endogenous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9155173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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