Article
[Molecular biology of the mechanism of acquisition of antimicrobial-resistance].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 2001
Hashimoto H
Abstract excerpt
There are two ways for a bacterium to acquire antimicrobial-resistance: 1) Horizontal transfer of resistance gene(s) from outside, 2) Mutation of its own chromosome. The former case includes conjugation, transduction and transformation. Resistance genes usually locate on transposon or integron and have inverted or direct repeats on both sides, or link to a special sequence at one side. A target of an antibiotic...
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