Article
The Role of Efflux Pumps in the Transition from Low-Level to Clinical Antibiotic Resistance
30 Nov 2020
Abstract excerpt
Antibiotic resistance is on the rise and has become one of the biggest public health challenges of our time. Bacteria are able to adapt to the selective pressure exerted by antibiotics in numerous ways, including the (over)expression of efflux pumps, which represents an ancient bacterial defense mechanism. Several studies show that overexpression of efflux pumps rarely provides clinical resistance but contributes...
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