Article
Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches.
Annual review of immunology - 1 Jan 1997
Constant S L, Bottomly K
Abstract excerpt
T helper lymphocytes can be divided into two distinct subsets of effector cells based on their functional capabilities and the profile of cytokines they produce. The Th1 subset of CD4+ T cells secretes cytokines usually associated with inflammation, such as IFN-gamma and TNF and induces cell-medi...
Topics
- Animals
- Antigens
- Antigens, Differentiation, T-Lymphocyte
- Cell Differentiation
- Collagen
- Cytokines
- Hematopoietic Stem Cells
- Humans
- In Vitro Techniques
- Ligands
- Peptides
- Phenotype
- Th1 Cells
- Th2 Cells