Article
Investigating genetic, antigenic, and structural diversity in the Neisseria gonorrhoeae outer membrane protein, PorB: implications for vaccine design.
mBio - 8 Oct 2025
Harrison Odile B, Bash Margaret, Ramirez-Bencomo Fidel, Thistlethwaite Angela, Jones Rebekah, Stejskal Lenka, Sanders Eduard, Feavers Ian M, Jerse Ann, Derrick Jeremy P, Tang Christoph M, Maiden Martin C J
Abstract excerpt
Vaccines targeting Neisseria gonorrhoeae are needed to reduce disease burden and help address the problem of antimicrobial resistance, with an understanding of relationships between gonococcal genetics and molecules influencing diversity, infection, and the immune response essential for developing effective vaccine formulations. Whole-genome sequence data can be used to investigate these relationships among...
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