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Article

The HypB protein from Bradyrhizobium japonicum can store nickel and is required for the nickel-dependent transcriptional regulation of hydrogenase.

Molecular microbiology - 1 Apr 1997

Olson J W, Fu C, Maier R J

Abstract excerpt

The HypB protein from Bradyrhizobium japonicum is a metal-binding GTPase required for hydrogenase expression. In-frame mutagenesis of hypB resulted in strains that were partially or completely deficient in hydrogenase expression, depending on the degree of disruption of the gene. Complete deletion of the gene yielded a strain (JH delta Eg) which lacked hydrogenase activity under all conditions tested, including...

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Source

Identifiers

PMID: 9140970
DOI: 10.1046/j.1365-2958.1997.3251690.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The HypB protein from Bradyrhizobium japonicum can store nickel and is required for the nickel-dependent transcriptional regulation of hydrogenase.PMID 9140970Read ↗

Dual roles of Bradyrhizobium japonicum nickelin protein in nickel storage and GTP-dependent Ni mobilization.Semantic proximity Read ↗

Identification of a locus within the hydrogenase gene cluster involved in intracellular nickel metabolism in Bradyrhizobium japonicum.Semantic proximity Read ↗

The sequences of hypF, hypC and hypD complete the hyp gene cluster required for hydrogenase activity in Bradyrhizobium japonicum.Semantic proximity Read ↗

Metal binding activity of the Escherichia coli hydrogenase maturation factor HypB.Semantic proximity Read ↗

Interaction between hydrogenase maturation factors HypA and HypB is required for [NiFe]-hydrogenase maturation.Semantic proximity Read ↗

The hydrogenase gene cluster of Rhizobium leguminosarum bv. viciae contains an additional gene (hypX), which encodes a protein with sequence similarity to the N10-formyltetrahydrofolate-dependent enzyme family and is required for nickel-dependent hydrogenase processing and activity.Semantic proximity Read ↗

Sequences and characterization of hupU and hupV genes of Bradyrhizobium japonicum encoding a possible nickel-sensing complex involved in hydrogenase expression.Semantic proximity Read ↗

Requirement of nickel metabolism proteins HypA and HypB for full activity of both hydrogenase and urease in Helicobacter pylori.Semantic proximity Read ↗

Involvement of hyp gene products in maturation of the H(2)-sensing [NiFe] hydrogenase of Ralstonia eutropha.Semantic proximity Read ↗

The FixK2 protein is involved in regulation of symbiotic hydrogenase expression in Bradyrhizobium japonicum.Semantic proximity Read ↗

Diversity and evolution of hydrogenase systems in rhizobia.Semantic proximity Read ↗

Duplication of hyp genes involved in maturation of [NiFe] hydrogenases in Alcaligenes eutrophus H16.Semantic proximity Read ↗

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