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Functional Roles of Immediate Early Proteins Encoded by the Human Cytomegalovirus UL36-38, UL115-119, TRS1/IRS1 and US3 Loci

1 Jan 1996

Abstract excerpt

Human cytomegalovirus (HCMV) encodes multiple regulatory proteins at immediate early (IE) times of infection. Ancillary IE proteins are encoded by the UL36-38, UL115-119, TRS1/IRS1 and US3 loci. In contrast to the major IE nuclear proteins, several of the ancillary IE proteins are type I integral membrane N-glycoproteins. Nonetheless, all of the ancillary proteins examined to date have the ability to regulate...

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PMID: 9130045
DOI: 10.1159/000150506

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