Article
Role of certain virulence factors in a murine model of Staphylococcus aureus arthritis.
Journal of medical microbiology - 1 Mar 1997
Gemmell C G, Goutcher S C, Reid R, Sturrock R D
Abstract excerpt
The susceptibility of male Swiss white mice (MF1) to Staphylococcus aureus-induced arthritis was investigated with wild-type strain allelic replacement mutants. Comparison was made with a known mouse arthritogenic strain. The development and severity of arthritis were dependent both on the numbers of live bacteria injected intravenously and also on the mutant used; the ID50 ranged from (5 X 10(6))-(1 x 10(8))...
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