Antibiotic‐Killed Staphylococcus aureus Induces Destructive Arthritis in Mice

doi:10.1002/art.38902

Article

Antibiotic‐Killed Staphylococcus aureus Induces Destructive Arthritis in Mice

9 Oct 2014

Abstract excerpt

OBJECTIVE: Permanent reduction in joint function is a severe postinfectious complication in patients with Staphylococcus aureus septic arthritis. We undertook this study to determine whether this reduction in joint function might be caused by persistent joint inflammation after the adequate eradication of bacteria by antibiotics. METHODS: After intraarticular injection of cloxacillin-killed S aureus into mouse...

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