Article
The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein.
Nature - 24 Apr 1997
Ackerman S L, Kozak L P, Przyborski S A, Rund L A, Boyer B B, Knowles B B
Abstract excerpt
Migration of neurons from proliferative zones to their functional sites is fundamental to the normal development of the central nervous system. Mice homozygous for the spontaneous rostral cerebellar malformation mutation (rcm(s)) or a newly identified transgenic insertion allele (rcm(tg)) exhibit cerebellar and midbrain defects, apparently as a result of abnormal neuronal migration. Laminar structure...
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