Environmental factors in the etiology of type 1 diabetes.

doi:10.1002/ajmg.10340

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Article

Environmental factors in the etiology of type 1 diabetes.

American journal of medical genetics - 30 May 2002

Akerblom Hans K, Vaarala Outi, Hyöty Heikki, Ilonen Jorma, Knip Mikael

Abstract excerpt

Type 1 diabetes is considered to be an autoimmune disease in which T lymphocytes infiltrate the islets of pancreas and destroy the insulin producing beta cell population. Besides antigen specificity, the quality of immune reactivity against islet cell antigen(s) is an important determinant of the beta cell destruction. Much evidence indicates that the function of the gut immune system is central in the...

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PMID: 12116173
DOI: 10.1002/ajmg.10340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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