Article
[Pharmacogenetics and its importance in the clinical].
Gaceta medica de Mexico - 1 Jan 2000
Lares-Asseff I, Trujillo-Jiménez F
Abstract excerpt
Therapeutic inefficacy and pharmacologic toxicity has frequently been seen in the clinical use of drugs or medicines in individuals under pharmacological treatment. Due to the presence of drug metabolizing enzymes, medicines may participate as substrate inhibitors or enzyme inductors. Their activity may vary among individuals. This enzymatic variability may be assessed through the analysis of recombinant DNA,...
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