[Pharmacogenetics and its importance in the clinical].

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Article

[Pharmacogenetics and its importance in the clinical].

Gaceta medica de Mexico - 1 Jan 2000

Lares-Asseff I, Trujillo-Jiménez F

Abstract excerpt

Therapeutic inefficacy and pharmacologic toxicity has frequently been seen in the clinical use of drugs or medicines in individuals under pharmacological treatment. Due to the presence of drug metabolizing enzymes, medicines may participate as substrate inhibitors or enzyme inductors. Their activity may vary among individuals. This enzymatic variability may be assessed through the analysis of recombinant DNA,...

Topics

Acetylation
Animals
Arylamine N-Acetyltransferase
Biotransformation
Chromatography, High Pressure Liquid
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
DNA, Recombinant
Drug-Related Side Effects and Adverse Reactions
Ethnicity
Genetic Predisposition to Disease
Genotype
Humans
Inactivation, Metabolic
Mexico
Microsomes, Liver
Pharmacogenetics
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 11432091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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