delta-Thalassemic phenotype due to two "novel" delta-globin gene mutations: CD11[GTC-->GGC (A8)-HbA2-Pylos] and CD 85[TTT-->TCT(F1)-HbA2-Etolia].

doi:10.1002/(SICI)1098-1004(1997)9:4<344::AID-HUMU7>3.0.CO;2-5

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Article

delta-Thalassemic phenotype due to two "novel" delta-globin gene mutations: CD11[GTC-->GGC (A8)-HbA2-Pylos] and CD 85[TTT-->TCT(F1)-HbA2-Etolia].

Human mutation - 1 Jan 1997

Drakoulakou O, Papapanagiotou E, Loutradi-Anagnostou A, Papadakis M

Abstract excerpt

delta-Thalassemia reduces the expected HbA2 percentage, altering the normal as well as the beta-thalassemia trait phenotype. An attempt to elucidate the molecular basis of delta-thalassemia in the Greek population, revealed two cases with unknown molecular defects that presented low levels of HbA...

Topics

Adult
DNA Mutational Analysis
Genes
Globins
Greece
Hemoglobin A2
Hemoglobins, Abnormal
Humans
Phenotype
Point Mutation
Thalassemia

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