Article
Analysis of δ-globin gene alleles in Tunisians: description of three new delta-thalassemia mutations.
Molecular biology reports - 1 Aug 2021
Kasmi Chaima, Amri Yessine, Hadj-Fredj Sondess, Oueslati Sabrine, Dabboussi Malek, Mahjoub Rahma, Hammami Sana, Aljane Imen, Mami Faika Ben, Jamoussi Henda, Messaoud Taieb, Bibi Amina
Abstract excerpt
BACKGROUND: Thalassemia is one of the most prevalent worldwide autosomal recessive disorders characterized by a great molecular and clinical expression heterogeneity. Alpha and beta-thalassemia are the main two types observed in case of mutations affecting alpha and beta-globin genes respectively. Delta-thalassemia is noted when mutations occur on the delta-globin gene. In Tunisia, β-thalassemia prevalence...
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