Article
HLA-DPB1 DNA polymorphism in the Swiss population: linkage disequilibrium with other HLA loci and population genetic affinities.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jun 1994
Grundschober C, Sanchez-Mazas A, Excoffier L, Langaney A, Jeannet M, Tiercy J M
Abstract excerpt
Allelic diversity at the HLA-DPB1 locus was determined by PCR-oligotyping in a sample of 125 healthy Swiss individuals. A total of 17 alleles were detected among which four main alleles (DPB1*0401, *0201, *0301, *0402) reached a cumulative frequency of 74.8%. HLA-A and -B (by serology) and HLA-DR...
Topics
- Alleles
- Chromosome Mapping
- DNA
- Gene Frequency
- HLA Antigens
- HLA-DP Antigens
- HLA-DP beta-Chains
- Haplotypes
- Humans
- Linkage Disequilibrium
- Polymorphism, Genetic
- Switzerland