Article
[Assessment of genetic toxicity of the exposure to clomiphene citrate, with various bacterial test systems].
Ginecologia y obstetricia de Mexico - 1 Nov 1996
Arriaga-Alba M, Flores-Paz R, Díaz-Hernández R, González-Patiño M E
Abstract excerpt
Clomiphene citrate (CC) induces framshift mutations on the Salmonella typhimurium Ames strains TA1538, TA97 and TA100 employing in vitro metabolic activation with S9 aerochlor 1254 induced rat livers, but not base pair substitution mutations with neither the standard or the preincubation method. CC induced genolethal DNA damages on the Escherichia coli PolA-/PolA+ with S9 on the preincubation method or without S9...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
