Prospects for quantitative trait locus methodology in gerontology.

Abstract excerpt

The remarkable advances in mapping of genomes have made it feasible to search among the hitherto anonymous polygenes of complex systems for loci of intermediate effect size (quantitative trait loci-QTL). Pursuing the strategy of identifying these QTL in complex systems will open the possibility of exploring the genetic architecture and the anatomical, physiological, biochemical, and molecular mechanisms...

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