Article
Evidence for genetic control of changes in f-actin polymerization caused by pathogenic microorganisms: in vitro assessment using gingival fibroblasts from human twins.
Journal of periodontal research - 1 Jan 1997
Hassell T M, Baehni P, Harris E L, Walker C, Gabbiani G, Geinoz A
Abstract excerpt
Attachment to and migration upon a substratum, as well as other functions of connective tissue cells, are regulated mainly by cytoplasmic structural proteins, particularly filamentous actin (f-actin). Pathogenic microorganisms exert negative effects on cytoskeletal proteins. In the present study,...
Topics
- Actins
- Adolescent
- Adult
- Bacterial Proteins
- Cell-Free System
- Cells, Cultured
- Child
- Disease Susceptibility
- Female
- Fibroblasts
- Fusobacterium nucleatum
- Genetic Predisposition to Disease
- Genetic Variation
- Gingiva
- Humans