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Article

Quantitation of actin polymerization in two human fibroblast sub-types responding to mechanical stretching.

Journal of cell science - 1 Sept 1991

Pender N, McCulloch C A

Abstract excerpt

To study early reorganization of the cytoskeleton in response to physical forces, human gingival and periodontal ligament fibroblasts were cultured on flexible plastic substrata and stretched by mechanical deformation of the substratum. F-actin was measured by quantitative spectrofluorimetry of FITC-phalloidin-stained cells. Fluorescence due to FITC-phalloidin was reduced stoichiometrically by co-incubation with...

Topics

Actins
Cells, Cultured
Fibroblasts
Fluorescence
GTP-Binding Proteins
Gingiva
Humans
Periodontal Ligament
Phenotype
Polymers
Stress, Mechanical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1795024
DOI: 10.1242/jcs.100.1.187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1795024-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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