Article
Priming effects of lipopolysaccharide on UTP-induced arachidonic acid release in RAW 264.7 macrophages.
European journal of pharmacology - 19 Feb 1997
Lin W W
Abstract excerpt
Stimulation of mouse RAW 264.7 macrophages with UTP activates both the inositol phosphate signal transduction pathway and the phospholipase A2 pathway. In the present study, we investigated the interactions between bacterial lipopolysaccharide and UTP in these two systems and the underlying mechanisms involved. While the UTP-induced release of arachidonic acid was only 2.9-fold that in controls, priming the cells...
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