Article
Bullous pemphigoid and linear IgA dermatosis sera recognize a similar 120-kDa keratinocyte collagenous glycoprotein with antigenic cross-reactivity to BP180.
The Journal of investigative dermatology - 1 Apr 1997
Pas H H, Kloosterhuis G J, Heeres K, van der Meer J B, Jonkman M F
Abstract excerpt
Circulating IgG from a large subset of bullous pemphigoid (BP) patients reacted on immunoblot with a 120-kDa protein in conditioned keratinocyte culture medium and in keratinocyte cell extracts. A protein with a similar molecular weight was recognized by circulating IgA from a subset of patients with linear IgA dermatosis (LAD). Both affinity-purified 120-kDa-specific BP IgG and 120-kDa-specific LAD IgA bound to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
