Article
Specific arrest of spermatogenesis caused by apoptotic cell death in transgenic mice.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Dec 1996
Suzuki M, Abe K, Yoshinaga K, Obinata M, Furusawa M, Abe K
Abstract excerpt
BACKGROUND: The c-myc protooncogene has been implicated in the control of cell proliferation, differentiation and/or apoptosis in various cellular systems. However, the role of c-myc in germ cell lineage is largely unknown. RESULTS: We have produced transgenic mouse lines carrying the rat c-myc protooncogene under the control of human metallothionein promoter (hMT-c-myc). It was found that the male transgenic...
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