Article
Specific arrest of spermatogenesis caused by apoptotic cell death in transgenic mice.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Dec 1996
Suzuki M, Abe K, Yoshinaga K, Obinata M, Furusawa M, Abe K
Abstract excerpt
BACKGROUND: The c-myc protooncogene has been implicated in the control of cell proliferation, differentiation and/or apoptosis in various cellular systems. However, the role of c-myc in germ cell lineage is largely unknown. RESULTS: We have produced transgenic mouse lines carrying the rat c-myc p...
Topics
- Animals
- Apoptosis
- Base Sequence
- Cell Differentiation
- Infertility
- Male
- Metallothionein
- Mice
- Mice, Transgenic
- Phenotype
- Promoter Regions, Genetic
- Proto-Oncogene Proteins c-myc
