Spontaneous Germ Cell Apoptosis in Humans: Evidence for Ethnic Differences in the Susceptibility of Germ Cells to Programmed Cell Death

Abstract excerpt

Spontaneous death of certain classes of germ cells has been shown to be a constant feature of normal spermatogenesis in a variety of mammalian species, including the human. Recent studies on various animal models have demonstrated that apoptosis is the underlying mechanism of germ cell death during normal spermatogenesis. Withdrawal of gonadotropins and/or testosterone further accelerates the germ cell apoptosis....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Reproductive Biology and Fertility
• Share to RNA Interference and Gene Delivery
• Share to Sperm and Testicular Function