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Expression of E-Cadherin, α-Catenin, β-Catenin and Plakoglobin in Esophageal Carcinomas and Its Prognostic Significance

30 Jun 2009

Abstract excerpt

It has been suggested that inactivation of the cadherin-mediated cell-cell adhesion system plays a role in the initial steps of cancer invasion and metastasis. Expression of E-cadherin and its intracytoplasmic binding molecules, alpha-catenin, beta-catenin and plakoglobin was examined immunohistochemically in 96 esophageal squamous cell carcinomas to investigate the association between their expression and the...

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PMID: 9075789
DOI: 10.1159/000227681

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