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Article

Hemochromatosis: association of severity of iron overload with genetic markers.

Blood cells, molecules & diseases - 1 Jan 1996

Barton J C, Harmon L, Rivers C, Acton R T

Abstract excerpt

We postulated that the severity of iron overload in homozygous hemochromatosis probands is related to the expression of HLA-A3 or D6S105 allele 8. Therefore, we used these markers to characterize Alabama hemochromatosis probands and normal control subjects. We then quantified the blood removed by phlebotomy to exhaust body iron stores and maintain normal serum ferritin concentrations in our hemochromatosis...

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Identifiers

PMID: 9075570
DOI: 10.1006/bcmd.1996.0100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Hemochromatosis: association of severity of iron overload with genetic markers.PMID 9075570Read ↗

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Hereditary hemochromatosis: a review of the genetics, mechanism, diagnosis, and treatment of iron overload.Semantic proximity Read ↗

The HLA-A1-B8 haplotype hitchhiking with the hemochromatosis mutation: does it affect the phenotype?Semantic proximity Read ↗

A study of 82 extended HLA haplotypes in HFE-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overload.Semantic proximity Read ↗

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