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Screening for Hereditary Hemochromatosis: A Clinical Practice Guideline from the American College of Physicians

4 Oct 2005

Abstract excerpt

Hereditary hemochromatosis is a genetic disorder of iron metabolism. Diagnosis of hereditary hemochromatosis is usually based on a combination of various genetic or phenotypic criteria. Decisions regarding screening are difficult because of the variable penetrance of mutations of the HFE gene and the absence of any definitive trials addressing the benefits and risks of therapeutic phlebotomy in asymptomatic...

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PMID: 16204164
DOI: 10.7326/0003-4819-143-7-200510040-00010

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