Article
Selection of retrovirally transduced cells to enhance the efficiency of gene therapy.
Proceedings of the Association of American Physicians - 1 Mar 1997
Medin J A, Karlsson S
Abstract excerpt
Retrovirally mediated gene transfer is the approach of choice for many laboratories interested in gene therapy. One problem, however, is that the efficiency of therapeutic gene transfer to some important target cells is low. A strategy employed by a number of investigators to overcome this shortcoming is to construct recombinant viruses that employ selection modalities. These strategies can be classified broadly...
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