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Article

Mutational analysis of the hMLH1 gene using an automated two-dimensional DNA typing system.

Human mutation - 1 Jan 1997

Sasaki S, Tokino T, Miyatsu T, Muto T, Nakamura Y

Abstract excerpt

Searching for mutations in DNA mismatch repair genes is important not only for presymptomatic diagnosis, but also for documenting the spectrum of mutations among families carrying predispositions to hereditary nonpolyposis colorectal cancer (HNPCC). We utilized an automated two-dimensional DNA typing system for mutational analysis of the hMLH1 gene and established optimal conditions for application of the...

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PMID: 9067757
DOI: 10.1002/(SICI)1098-1004(1997)9:2<164::AID-HUMU9>3.0.CO;2-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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