Article
Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry.
Journal of virology - 1 Apr 1997
Chen Z, Zhou P, Ho D D, Landau N R, Marx P A
Abstract excerpt
Entry of human immunodeficiency virus type 1 (HIV-1) requires CD4 and one of a family of related seven-transmembrane-domain coreceptors. Macrophage-tropic HIV-1 isolates are generally specific for CCR5, a receptor for the CC chemokines RANTES, MIP-1alpha, and MIP-1beta, while T-cell line-tropic v...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Cell Line, Transformed
- Conserved Sequence
- DNA
- Gene Products, env
- Genetic Variation
- Humans
- Macaca mulatta
- Membrane Fusion
- Molecular Sequence Data
- Phenotype
- Receptors, CCR5
- Receptors, Cytokine
- Receptors, HIV
- Receptors, Virus