Article
The U(L)15 gene of herpes simplex virus type 1 contains within its second exon a novel open reading frame that is translated in frame with the U(L)15 gene product.
Journal of virology - 1 Apr 1997
Baines J D, Cunningham C, Nalwanga D, Davison A
Abstract excerpt
The U(L)15 gene of herpes simplex virus type 1 is composed of two exons. A mutation previously shown to preclude viral DNA cleavage and packaging at the nonpermissive temperature was identified as a change from a highly conserved serine to proline at codon 653. Separate viral mutants that contain...
Topics
- Animals
- Capsid
- Chlorocebus aethiops
- DNA, Viral
- Exons
- Genes, Viral
- Herpesvirus 1, Human
- Humans
- Molecular Weight
- Mutagenesis
- Open Reading Frames
- Phenotype
- Protein Biosynthesis
- Rabbits
- Temperature
- Tumor Cells, Cultured
- Vero Cells
- Viral Envelope Proteins