Molecular basis of asymptomatic beta-thalassemia major in an African American individual.

Article

Molecular basis of asymptomatic beta-thalassemia major in an African American individual.

American journal of medical genetics - 17 Mar 1997

Ballas S K, Cai S P, Gabuzda T, Chehab F F

Abstract excerpt

The beta-thalassemia syndromes are a heterogeneous group of genetic disorders characterized by reduced or absent expression of the beta-globin gene. To date, over 300 beta-thalassemia alleles have been characterized in or around the beta-globin region. Thalassemia major is severe anemia necessita...

Topics

Female
Haplotypes
Humans
Middle Aged
Mutation
Nucleic Acid Hybridization
Polymerase Chain Reaction
Polymorphism, Genetic
Syndrome
beta-Thalassemia

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