Article
Computation of multilocus prior probability of autozygosity for complex inbred pedigrees.
Genetic epidemiology - 1 Jan 1997
Guo S W
Abstract excerpt
Homozygosity mapping is a very powerful method for mapping rare recessive diseases in humans. In many applications, it is often desirable to compute prior (or unconditional) multilocus probability of autozygosity for inbred pedigrees. This paper proposes a simple yet powerful method for computing the prior multilocus autozygosity probability for complex inbred pedigrees. The method has an added feature of...
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