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Article

Analysis of complex human genetic traits: an ordered-notation method and new tests for mode of inheritance.

American journal of human genetics - 1 Aug 1995

Thomson G

Abstract excerpt

A novel ordered notation is introduced that allows description and calculation of the probability of any nuclear-pedigree configuration of disease status and marker-allele information. Algorithms are given that allow for complex models of disease predisposition, a highly polymorphic or less polymorphic marker locus, gametic disequilibrium between the marker and disease loci (marker association with disease),...

Topics

Alleles
Chromosome Mapping
Computer Simulation
Genetic Linkage
Humans
Lod Score
Models, Genetic
Pedigree

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7668274
PMCID: PMC1801559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7668274-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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