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Article

The haploinsufficient Col3a1 mouse as a model for vascular Ehlers-Danlos syndrome.

Veterinary pathology - 1 Nov 2010

Cooper T K, Zhong Q, Krawczyk M, Tae H-J, Müller G A, Schubert R, Myers L A, Dietz H C, Talan M I, Briest W

Abstract excerpt

Vascular Ehlers-Danlos syndrome is a rare genetic disorder resulting from mutations in the α-1 chain of type III collagen (COL3A1) and manifesting as tissue fragility with spontaneous rupture of the bowel, gravid uterus, or large or medium arteries. The heterozygous Col3a1 knockout mouse was inve...

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Identifiers

PMID: 20587693
DOI: 10.1177/0300985810374842
PMCID: PMC2970629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20587693-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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