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Article

Spermatozoa lacking acrosin protein show delayed fertilization

1 Mar 1997

Abstract excerpt

Acrosin (ACR), a serine proteinase located in the acrosome of the sperm, has been presumed to be involved in the recognition and binding of the sperm to the zona pellucida of the ovum and the sperm penetration through the zona pellucida. To examine the function of acrosin in vivo, we have generated mice carrying a mutation at the acrosin locus (Acr) through targeted disruption in embryonic stem (ES) cells. One...

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Identifiers

PMID: 9041140
DOI: 10.1002/(sici)1098-2795(199703)46:3<370::aid-mrd16>3.0.co;2-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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