Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.

Nature - 27 Feb 1997

Brunner E, Peter O, Schweizer L, Basler K

Abstract excerpt

Members of the Wnt/Wingless (Wg) family of signalling proteins organize many aspects of animal development by regulating the expression of particular target genes in responding cells. Recent biochemical studies indicate that the vertebrate HMG-domain proteins Lef-1 and XTcf-3 can physically interact with beta-catenin, a homologue of Drosophila Armadillo (Arm), the most downstream component known in the Wnt signal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to DNA-Binding Proteins
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Protein Binding

Share to Signal Transduction

Source

Identifiers

PMID: 9039917
DOI: 10.1038/385829a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.PMID 9039917Read ↗

dTcf/Pangolin suppresses growth and tumor formation in DrosophilaSemantic proximity Read ↗

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF.Semantic proximity Read ↗

Drosophila Wnt/Fz pathways.Semantic proximity Read ↗

Dissecting nuclear Wingless signalling: recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins.Semantic proximity Read ↗

Components of wingless signalling in Drosophila.Semantic proximity Read ↗

In pursuit of the functions of the Wnt family of developmental regulators: insights from Xenopus laevis.Semantic proximity Read ↗

Wnt, Hedgehog and junctional Armadillo/beta-catenin establish planar polarity in the Drosophila embryo.Semantic proximity Read ↗

Drosophila Segment Polarity Mutants and the Rediscovery of the Hedgehog Pathway Genes.Semantic proximity Read ↗

Trunk-specific modulation of wingless signalling in Drosophila by teashirt binding to armadillo.Semantic proximity Read ↗

The armadillo family of structural proteins.Semantic proximity Read ↗

Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan.Semantic proximity Read ↗

The ciD mutation encodes a chimeric protein whose activity is regulated by Wingless signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.