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Article

A novel 3'-end repair mechanism in an RNA virus.

Proceedings of the National Academy of Sciences of the United States of America - 18 Feb 1997

Nagy P D, Carpenter C D, Simon A E

Abstract excerpt

Many positive-stranded RNA viruses contain short, single-stranded 3' ends that are vulnerable to degradation by host cellular RNases. Therefore, the existence of a 3'-end repair mechanism (analogous to cellular telomerases) must be required and/or advantageous for RNA viruses. Accordingly, we provide evidence suggesting that deletions of up to 6 nt from the 3' end of satellite (sat-) RNA C (a small parasitic RNA...

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Identifiers

PMID: 9037015
DOI: 10.1073/pnas.94.4.1113
PMCID: PMC19753

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