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Article

Epigenetic modification of TLRs in leukocytes is associated with increased susceptibility to Salmonella enteritidis in chickens.

PloS one - 1 Jan 2012

Gou Zhongyong, Liu Ranran, Zhao Guiping, Zheng Maiqing, Li Peng, Wang Huihua, Zhu Yun, Chen Jilan, Wen Jie

Abstract excerpt

Toll-like receptors (TLRs) signaling pathways are the first lines in defense against Salmonella enteritidis (S. enteritidis) infection but the molecular mechanism underlying susceptibility to S. enteritidis infection in chicken remains unclear. SPF chickens injected with S. enteritidis were partitioned into two groups, one consisted of those from Salmonella-susceptible chickens (died within 5 d after injection, n...

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Source

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Identifiers

PMID: 22438967
DOI: 10.1371/journal.pone.0033627
PMCID: PMC3306431

Genes

TLR2
TLR4
TOLLIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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