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Article

Transfection with aFGF cDNA Improves Wound Healing

1 Mar 1997

Abstract excerpt

Somatic gene therapy is a potentially useful strategy for the delivery of growth factors or cytokines to enhance wound healing. Experimental excisional and incisional wounds in impaired-healing diabetic mice (db/db) were treated with aFGF and with a plasmid coding for aFGF. A eukaryotic expression plasmid composed of the Hst signal peptide sequence in-frame with the human aFGF sequence was used. Transfection of...

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PMID: 9036931
DOI: 10.1111/1523-1747.ep12286471

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